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Graphite laminate with insert with Arsenic trichloride. A. -. -. -. -.

Arsenic trioxide package insert

It may occur in as many as 25% of patients. A package insert typically includes information regarding specific indications, administration schedules, dosing, side effects, contraindications, results from some clinical trials, chemical structure, pharmacokinetics and metabolism of the specific drug.By carefully reviewing the package insert, you will get the most complete and current information about how to safely use this drug. Browse our range of sterile injectable, oral solid and other products. SteriMax is committed to improving the wellness Canadians. Arsenic Trioxide// Arsenic trioxide is a chemotheraputic agent of idiopathic function used to treat leukemia that is unresponsive to first line agents. It is suspected that arsenic trisulfide induces cancer cells to undergo apoptosis.

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Arsenic trioxide serious interactions with 73 different drugs. Arsenic trioxide has moderate interactions with 34 different drugs. Arsenic trioxide has no listed mild interactions with other drugs.

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Elimination is rapid at first (half-life of 1–2 days), by methylation to monomethylarsonic acid and dimethylarsonic acid, and excretion in the urine, but a certain amount (30–40% in the case of repeated exposure) is incorporated into the bones, muscles, skin 2019-08-29 · TRISENOX is formulated as a sterile, nonpyrogenic, clear solution of arsenic trioxide in water for injection using sodium hydroxide and dilute hydrochloric acid to adjust to pH 8. TRISENOX is preservative-free.

See full prescribing information for TRISENOX. TRISENOX® (arsenic trioxide) injection, for intravenous use Initial U.S. Approval: 2000 WARNING: DIFFERENTIATION SYNDROME, Arsenic trioxide also causes damage or 20 degradation of the fusion protein PML-RAR alpha. 21 Pharmacokinetics 22 The pharmacokinetics of trivalent arsenic, the active species of TRISENOX™, has not been 23 characterized.
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Arsenic Trioxide (Trisenox®) Arsenic trioxide is an intravenous infusion typically infused over 1 to 2 hours each day it is given; Retinoic acid syndrome (or APL differentiation syndrome) may occur anytime during the first month of treatment with arsenic. It may occur in as many as 25% of patients. A package insert typically includes information regarding specific indications, administration schedules, dosing, side effects, contraindications, results from some clinical trials, chemical structure, pharmacokinetics and metabolism of the specific drug.By carefully reviewing the package insert, you will get the most complete and current information about how to safely use this drug.

November 2008. Other: Recommendations for the Safe Handling of Parenteral Antineoplastic Drugs. Publication NIH 83-2621. For sale by the Superintendent of Documents, U.S. Government Printing Office, Washington, DC 20402.
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APL is a rare form of leukaemia (cancer of the white blood cells) caused by a genetic ‘translocation’ (when there is a swap of genes between two chromosomes).